Leanne Nantais-Smith, PhD, RN, NNP-BC
Associate Professor Clinical, Director of Advanced Practice and Graduate Certificate Programs, Graduate Specialty Coordinator, Neonatal Nurse Practitioner Specialty240 Cohn
Leanne Nantais-Smith, PhD, RN, NNP-BC
Program of Research titleIdentification of Noninvasive Biomarkers of Necrotizing Enterocolitis in Extremely Preterm Infants
My research is focused on improving care of the preterm infant with necrotizing enterocolitis, specifically identifying noninvasive biomarkers that will improve management of infants with this disease in order to improve outcomes and decrease mortality and morbidity.
Populations of interests
- Preterm infants
- All populations
- All specialties, focus NNP
- Neonates and families
Program of Research
Leanne Nantais-Smith Ph.D., RN, NNP-BC, College of Nursing Associate Clinical Professor at Wayne State University, has focused her research on identification of noninvasive biomarker to diagnose and validate recovery from necrotizing enterocolitis (NEC), an inflammatory bowel disease in extremely preterm infants. Identification of these markers will improve management of infants with NEC and improve outcomes. Her pilot study, which was funded by the Ada Jacox Research Award and the College of Nursing Research Award, focused on the feasibility of measuring specific noninvasive biomarkers in small urine and stool samples collected at time of NEC diagnosis. Phase II of the NEC Biomarker study will focus on multi-center prospective noninvasive sample collection from extremely preterm infants for investigation of biomarkers for diagnosis and the recovery phase of NEC.
Leanne Nantais-Smith PhD, RN, NNP-BC, College of Nursing Associate Clinical Professor at Wayne State University, has extensive experience as a Neonatal Nurse Practitioner and has focused her research on the identification of noninvasive biomarkers of necrotizing enterocolitis in extremely preterm infants. She has served as a member of the National Association of Neonatal Nurse Practitioners Task Force for the 2008 and 2014 published national Education Standards and Curriculum Guidelines for NNP Education. She has also co-authored articles on NNP workforce shortage issues, NICU case reports and case-based education, a continuing education NICU module, and parent decision-making with extremely preterm infants.
- BSN – Michigan State University, East Lansing, Michigan
- MSN – Wayne State University, Detroit, MI
- PhD Nursing – Wayne State University, Detroit, MI
Clinical Area(s) of Expertise
- Noninvasive NEC Biomarker research
- Development of NNP Education Standards and Curriculum Guidelines
- NNP Clinical Specialty Education
Publications (*data based; †with student)
Nantais-Smith, L.M. & Herrington, C.J. (2016). Chapter 4: "Assessing Growth Parameters in the Newborn: Identifying Abnormal Findings." In Neonatal Advanced Practice Nursing: A Case-Based Learning Approach. Springer Publishing Company: New York
Herrington, C.J. & Nantais-Smith, L.M. (2016). "Noninvasive ventilation in the preterm infant." CNE Now! National Association of Neonatal Nurses. Chicago, IL.
*Nantais-Smith, L. & Kadrofske, M. (2015). "Non-Invasive Biomarkers of NEC." Journal of Perinatal and Neonatal Nursing, 29(1), January-March.
*Freed, G.L., Dunham, K.M., Martyn, K., Nantais-Smith, L., Moran, L.M., & Spera, L. (2015). "Capacity of, and Demand for, Neonatal Nurse Practitioner Educational Programs: A missing piece of the workforce puzzle." Journal of Professional Nursing, 31(4), July-August.
†Ohns M.J., Oliver-McNeil, S., Nantais-Smith, L. M., & George, N. (2015). "Nonurgent use of the emergency department by pediatric patients: A theory-guided approach for primary and acute care pediatric nurse practitioners." Journal of Pediatric Health Care, 30(4), 339-346.
*Kavanaugh, K., Nantais-Smith, L., Savage, T., Schim, S.M., & Natarajan, G. (2014). "Extended Family Support for Parents Faced with Life Support Decisions for Extremely Premature Infants." Neonatal Network, 33(5), September/October 2014. Springer Publishing Company,
Task Force. Contributing Author. (2014, February). Education Standards and Curriculum Guidelines. National Association of Nurses (NANN); Glenview, Illinois.
*Freed, G.L., Dunham, K.M., Martyn, K., Nantais-Smith, L., Moran, L.M., & Spera, L. (2013). "Neonatal Nurse Practitioners: Influence on Career Choice." Journal of Nurse Practitioners, 9(2), 82-86.
*Ennis, B. & Nantais-Smith, L. (2010). "Visual Diagnosis: Lower Lumbosacral Cutaneous Lesion in a Newborn." NeoReviews, January 2010; 11:e44.
Honors and Awards
2015 WSU President’s Award for Excellence in Teaching
Nantais-Smith. L. Noninvasive Biomarkers of Necrotizing Enterocolitis: A Pilot Study. 2012-2015: Ada Jacox Research Award ($5,000) and College of Nursing Dean’s Research Award ($6,999).
- NUR 7444 Advanced Physiology and Pathophysiology Across the Lifespan
- NUR7200 Advanced Neonatal Pharmacology
- NUR 7030 Advanced Nursing Assessment
- NUR 7225 Pathophysiology, Clinical Care, and Management I: Neonatal Nurse Practitioner Specialty
- NUR 7226 Pathophysiology, Clinical Care, and Management II: Neonatal Nurse Practitioner Specialty
- NUR 7227: Pathophysiology, Clinical Care, and Management III: Neonatal Nurse Practitioner Specialty
- NUR 8650 Advanced Practice Leadership