Research studies are motivated by the investigator’s insights, patient’s needs, and health care system dynamics. Advances in statistical methodology and research design make it possible to address more complex and important questions today than ever before.

Program of Research

I work with the PI and team members to fashion an approach that takes advantage of modern statistical research design methodology and to formulate specific questions that will advance the PIs program of research. This collaboration results in a kind of partnership that is built in the process of attaining funding, responding to reviewer’s critiques, and carrying out the analyses once significant funding is secured. I have been fortunate to have worked with many different teams over the years. Several have involved multiple cycles of NIH funding. From these collaborations and partnerships I have coauthored more than 150 peer reviewed articles.

The co-authored articles include examples of advanced statistical methodology:
• multi-arm adaptive clinical trials with multilevel modeling,
• cross-sectional and longitudinal designs with structural equation modeling,
• psychometric designs with IRT, CFA, and bifactor models, and
• hierarchical agglomerative clustering

Dr. Templin’s research interest is in cross-disciplinary statistical methodology and research design including the integration of qualitative and quantitative data.

Current Research

Title: Effectiveness Trial of an E-Health Intervention to Support Diabetes Care in Minority Youth
PI: Deborah Ellis, Agency: NIH/NIDDK, Dates: 04/01/2017-3/31/2022
Type: R01DK110075-01A1, My role: Senior statistician, Calendar months: .6
Total costs: $3,050,831.00
The purpose of the proposed study is to conduct a multicenter trial of a brief computer-delivered intervention aimed at increasing parental motivation for monitoring youth diabetes care among parents of AA adolescents who are beginning to transition to independent self-care and to assess factors affecting intervention adoption in real-world diabetes clinics.

Title: Translating an Efficacious Illness Management Intervention for African American Youth with Poorly Controlled Asthma to Real World Settings
PI: Deborah Ellis, Agency: NIH/NHLBI, Dates: 08/20/2017-06/30/2022
Type: 1R01HL138633-01A1, My role: Senior statistician, Calendar months: .6
Total costs: $3,223,883.00
The purpose of this study is to develop interventions to reduce barriers to optimal asthma management and reduce the risk for asthma-related deaths of minority children, with a focus on African American adolescents. The project will adapt and test an evidence-based intervention for use in pediatric emergency rooms and evaluate factors that affect whether the intervention is likely to be used in real-world settings.

Title: Social Stressors, Inflammation, and Preterm Birth: A Mixed Methods Approach
PI: Carmen Giurgescu, Agency: NIMHD, Dates: 01/06/2017- 12/31/2021,
Type: R01 MD011575 01A1,
Role: Co-I, Statistician, Calendar months: 1.2 (yrs1-4), 2.4 (yr 5)
Total costs: apx $250,000,000
The purpose of this project is to determine how social stressors alter inflammation during pregnancy and lead to PTB in African American women. Social stressors, psychosocial resources, and emotional stress will be measured by structured interviews and administrative (e.g., census) data.

Title: Motivational Enhancement System for Adherence (MESA) in Youth Starting ART
PI: Angulique Outlaw, Agency: NIH/NIMH, Dates: 08/01/2015 – 04/30/2020
Type: R01 MH108442 02, Role: Co-I, Senior Biostatistician, Calendar months: .60 in Years 1 – 3; and 1.20 in Years 4 and 5, Total direct costs: $2,032,125
The purpose of this study is to test a brief, two-session, computer-based intervention, based on the Information-Motivation-Behavioral Skills model and Motivational Interviewing principles, to prevent adherence difficulties among youth newly prescribed

Title: Michigan Center for Urban African American Aging (MCUAAAR)
PIs: James Jackson (UM) & Peter Lichtenberg (WSU). Agency: NIA, Type: 2P30AG015281-18, Dates: 09/01/12 – 08/31/17. Total cost of support apx $3,000,000. Role: Core faculty, .4 calendar.
The purpose of this research initiative is to decrease the minority/non-minority differential in health and aging research. This funding enables mentoring and financial support for pilot projects in diversity aging research for early career African American and ethnic minority scholars. It provides a network of opportunity for scholars to engage with established faculty in a cross-disciplinary and trans-university setting.

Title: Targeting PM to Improve HIV Adherence in Adolescents At Risk for Substance Abuse
PI/CoPI: Naar-King/Woods, Agency: NIH, Period: 07/01/12 – 06/30/17,
Type: 1 R01 DA034497 01, Direct Costs: $1,853,890, Role: Co-I, Statistician, .6 calendar (yrs 2-5).
This project proposes to test an intervention using SMS text messaging technology to promote medication adherence among youth and young adults living with HIV who are newly starting ART therapy.

Recently Completed

Title: Improving Functional Status in African Americans with Cancer Pain
PI: April Vallerand, Agency: National Cancer Institute, Type: RCA149432A
Period: 04/01/2011 – 03/31/2015, Total Cost: $895,104, Role: Co-I/Statistician, 2.4 calendar
The major goals of this project are to test a nursing intervention to increase pain relief among individual cancer patients and their families while also reducing systemic disparities in access, treatment and outcomes for African Americans

Title: Health Consequences of Adolescent Water Pipe Smoking With and Without Cigarette Smoking
PI: Virginia Hill Rice (10/01/12-11/5/2015), Thomas Templin (11/6/2015 – 7/31/2016) change in PI, no cost extension) , Agency: NIH NIDA, Type:1 R15 DA032822 01, Period: 10/01/12 – 7/31/2016,
Total Costs: $440,000, Role: Co-I, Statistician, 1.2 calendar.
This project will examine the effects of water pipe and cigarette smoking that was initiated during adolescence and effects on pulmonary functioning in young adults. Early initiation of smoking may stunt lung growth and this could be detected at a young age as early evidence of adverse health effects of tobacco use.

Title: Reducing Stress in Adolescents and Young Adults with T1D to Improve Diabetes Care
PI: Deborah Ellis, Agency: NIH NIDDK
Type: DP3 DK097717 01, Period: 9/21/2012 -8/31/2016, Total Cost: $2,343,122
Role: Statistician, 1.2 calendar
This project will (1) develop stress management interventions targeting objectively assessed stressors (e.g., conflict, noise) related to cortisol and diabetes management, (2) compare a cognitive-behavioral approach to a mindfulness-based intervention in a small pilot, and (3) execute a pilot randomized trial of the superior intervention to provide effect size information for a larger trial.

Title: Interventionist Procedures for Adherence to Weight Loss Recs in Black Adolescents
Co-PIs: S. Naar-King & Jen, Agency: National Heart, Lung, and Blood Institute
Type: 5U01HL097889, Period 09/28/2009 – 06/30/2015, Total Cost: $5,645,204
Role: Co-I/Statistician; 10% yrs. 1-3, 20% yrs. 4-5, 1.2 Calendar (2014-2015)
This research will develop and test interventions to reduce weight in high risk adolescents.
Title: Rater and Intensity Psychometrics of the Respiratory Disease Observation Scale
PI: Margaret Campbell, Agency: NIH National Institute of Nursing Research (NINR), Type: 1R03 NR012820-01A1, Period: 02/01/12-01/31/14, Direct Cost: $100,000, Role: Co-I/Statistician (Year 1: 0.6 calendar months (5%), Year 2: 1.2 calendar months (10%).
The purpose of this research is to validate the Respiratory Disease Observation Scale for use with nonprofessional and family member raters and to establish critical cut points for clinical intervention.

Title: Psychometric testing of the revised Beliefs about Personal Weight Survey. Agency: Sigma Theta Tau Award (June 2014). PI: Stephanie Pickett
The PI’s prior research identified four underlying dimensions in the Beliefs about Personal Weight Survey. This study developed new survey questions that matched the factor results. The new questionnaire was administered to a sample of 200 African American women. It is expected that a brief four-factor instrument will be predictive of BMI and eating behaviors.

 

Populations of interests

• Those of College of Nursing Principal Investigators.

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